HOWARU® Formulations

Brand success begins with quality formulations.

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Personalized Formulations

Let our renown probiotic experts help you create superior customized formulations. Whether you need to bounce an idea off us or you require more involved technical support, our probiotic experts are here to help. We listen to your needs and work with you to identify the best probiotic solution for your intended purpose. We’ll apply decades of experience and guide you in the proper selection of the most appropriate strains, excipients, processing aids, flavors and even prebiotic options to meet your needs.

Applications

Probiotics are used in a growing number of cutting-edge applications. We can advise you on which format to choose (i.e. capsules, sachets, chewables, gummies and more) and the requirements for ensuring optimum probiotic efficacy and survival during shelf life. We will keep you on the cutting edge with insight into the latest probiotic application and finished format innovations. We also are in the unique position to help support probiotic fortified food and beverage products as well.

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Wellness Concepts

Looking for a product that’s market ready? Explore our Wellness Solutions. These pre-formulated probiotic and vitamin blends are backed by science and marketing intelligence to meet the needs of consumers today. Whether you want to launch them as they are, customize them to your needs, or merely take them as inspiration for a brand-new concept, HOWARU® is your innovation partner.

 

Regulatory Support

Our probiotic cultures are internationally recognized as safe for consumption. But, when it comes to dosage levels and potential health claims, legislation can vary by country. Our regulatory team can help advise you on what individual markets permit. Our global regulatory experts are located in all major regions and provide you with access to a critical resource unrivaled in the industry

 

INTIMATE HEALTH Formulations

HOWARU® PROTECT PRENATAL+

HOWARU® Protect Prenatal+ supports the health of mother and child during pregnancy and beyond. This clinically-studied product not only promotes vaginal health but also happiness and calmness in new mothers. In addition, this combination of strains has also been shown to support healthy immune function in both mothers and their infants.

15B CFU | 6B HOWARU® Lacticaseibacillus rhamnosus HN001™ + 9B Lactobacillus acidophilus (HOWARU La-14™)

Benefits

  • Supports the immune health of expectant mothers and their infants
  • Helps promote healthy blood glucose levels in pregnant women
  • Supports positive postpartum mood
  • Helps maintain a healthy vaginal microbiota and pH

 

HOWARU® FEMININE HEALTH

HOWARU® Feminine Health features clinically-documented probiotic strains for vaginal health and overall feminine wellness. This formulation has been shown to promote healthy vaginal microbiota in addition to having beneficial effects regarding bacterial vaginosis and vulvovaginal candidiasis when administered in conjunction with metronidazole or clotrimazole treatment, respectively

10B CFU | HOWARU® Lacticaseibacillus rhamnosus HN001™ + Lactobacillus acidophilus (HOWARU La-14™) 

Benefits

  • Formulated exclusively for women’s vaginal health and wellness
  • Helps maintain healthy vaginal microbiota and pH
  • Results seen in 7 days* (*colonization of probiotic species observed in 7 days)

 

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Brain HEALTH Formulations

HOWARU® CALM

HOWARU® Calm is an innovative probiotic solution to promote calmness in adults. .

17B CFU | Lacticaseibacillus paracasei (HOWARU Lpc-37™)

Benefits

  • Helps to manage the  psychological response to stress
  • Promotes mental well-being
  • Helps balance and regulate general feelings of stress

 

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Digestive Health Formulations

HOWARU® DOPHILUS

HOWARU® Dophilus features Lactobacillus acidophilus NCFM®, a human intestine isolate supported by numerous research publications and which was the first Lactobacillus acidophilus strain for which the complete genomic sequence has been obtained. Its clinical studies began in the 1970s and have since had more than 300 research papers published on it, which have confirmed that this bacterium can help maintain a healthy intestinal environment.

 

1B CFU | Lactobacillus acidophilus (HOWARU NCFM™)

Benefits

  • Supports digestive health

 

HOWARU® TRANSIT

HOWARU® Transit is an evidence-based product studied to effectively shorten colonic transit time, support healthy digestion, and ease digestive discomfort including occasional gas and bloating. It was granted a health claim for supporting digestion by reducing gut transit time in Canada, Japan, Switzerland, and Brazil

2B CFU | HOWARU® Bifidobacterium lactis HN019™

Benefits

  • Helps maintain regularity
  • Helps to relieve occasional constipation and gas* (include footnote *not intended for chronic constipation)
  • Supports gut comfort

 

HOWARU® BALANCE

HOWARU® Balance is specifically designed to support digestive and immune health in adults ages 18-55. This unique formulation has been extensively studied in vitro and in animal models for characteristics considered to be important to digestive health. In addition, B. lactis HN019™ has been clinically proven in multiple human trials to demonstrate significant improvement in markers of immune health, suggesting that it contributes to strengthening the body’s natural defenses.

5B CFU | Lactobacillus acidophilus NCFM® + 5B CFU | Bifidobacterium lactis HN019™

Benefits

  • Supports healthy digestion
  • Promotes overall gut comfort
  • Supports healthy immune response

 

HOWARU® RESTORE

HOWARU® Restore is a documented probiotic blend shown to help replenish beneficial bacteria lost during times of dysbiosis. Its unique benefits are attributed to its formulation, which is comprised of equal amounts by number of bacteria adapted to upper intestine support as well as lower intestine support. This clinically-proven formulation has been shown to not only quickly promote digestive regularity but also restore overall digestive comfort.

17B CFU | Lactobacillus acidophilus (HOWARU NCFM™) + Lacticaseibacillus paracasei  (HOWARU Lpc-37™) + Bifidobacterium lactis (HOWARU Bi-07™ ) + Bifidobacterium  lactis (HOWARU Bl-04™)

Benefits

  • Supports gut health
  • Addresses duration of diarrhea
  • Lessens days of gut disruption

 

HOWARU® GI COMPLETE
HOWARU® GI Complete is a unique probiotic blend formulated with five clinically studied strains to improve overall gastrointestinal well-being and help relieve the most common digestive symptoms.

The probiotic strains of HOWARU® GI Complete are substantiated by several clinical studies1, supporting their remarkable benefits for digestive health.

HOWARU® GI Complete has also been tested and demonstrated in a consumer perception study in which participants have evaluated its efficacy on symptoms related to diarrhea, abdominal discomfort, bloating, gas and constipation. In this study, 85% of participants reported an improvement in their overall gastrointestinal well-being after 30 days2.

12B CFU | L. acidophilus (HOWARU NCFM™) + L. paracasei (HOWARU Lpc-37™) + B. lactis (HOWARU Bi-07™ ) + B. lactis (HOWARU Bl-04™) + B. lactis HN019™ (HOWARU HN019™)

Benefits

  • Address duration of diarrhea
  • Help relieve occasional constipation*
  • Help reduce gas
  • Promote abdominal comfort

1-Ouwehand et al. 2014; Ahmed et al. 2007, Gill et al. 2001a, Gill et al. 2001b, Miller et al. 2017 ; Waller et al. 2011, Supported by Ibarra et al. 2018
2-Harris et al., J Clin Gastroenterol Volume 56, Number 5, 2022
*not intended for chronic constipation

HOWARU® KIDS DIGESTIVE HEALTH

HOWARU® Kids Digestive Health is a delicious way for children to support their overall digestive wellness. Each berry-flavored chewable features 2.5 billion CFU of B. lactis HN019™, a probiotic strain shown to maintain gut health in children.

5B CFU | HOWARU® Bifidobacterium lactis HN019™

Benefits

  • Maintains gut health in children
  • Lessens gut disruption with daily intake in children
  • Supports digestive health in children

 

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Immune Health Formulations

HOWARU® PROTECT EARLYLIFE

HOWARU® Protect EarlyLife is a safe and proven probiotic formulation that supports the development of the immune system in infants. It has been clinically studied to support overall immunity in infants and children, with documented benefits spanning from birth through age 11.

6B CFU | HOWARU® L. rhamnosus HN001™

Benefits

  • Supports immune health to help build baby’s natural defenses
  • Continually supports infant’s and child’s immune system, year after year
  • Provides increased levels of healthy bacteria in the intestinal tract of infants

 

HOWARU® PROTECT KIDS

HOWARU® Protect Kids is a safe and proven probiotic formulation that supports the development of the immune system in infants. It has been clinically studied to support overall immunity in infants and children, with documented benefits spanning from birth through age 11.

 

10B CFU | 5B CFU Bifidobacterium lactis (HOWARU Bi-07™) + 5B CFU Lactobacillus acidophilus (HOWARU NCFM™)

Benefits

  • Helps promote optimal health and wellness in children
  • For maintenance of respiratory health in children
  • Helps shorten duration of symptoms and supports fewer missed school days

 

HOWARU® PROTECT ADULT

HOWARU® Protect Adult is a proven probiotic solution for supporting overall immune health in adults. It features one well-documented strain for immune health, Bifidobacterium lactis Bl-04®, which research has shown to also bolster healthy respiratory function in adults

 

2B CFU | Bifidobacterium lactis (HOWARU Bl-04™)​

Benefits

  • Promotes a healthy immune response
  • Helps maintain healthy respiratory function
  • Helps active adults stay healthy

 

HOWARU® PROTECT 55+

HOWARU® Protect 55+ is designed to promote immune enhancement in aging adults. Bifidobacterium lactis HN019™ is supported by a long list of successful clinical studies on the health of the immune system in seniors, and is regarded as a natural, safe, and efficacious way to for the aging population to stay healthy.

 

5B CFU | HOWARU® Bifidobacterium lactis HN019™

Benefits

  • Helps maintain a healthy, active immune system
  • Shifts microbial balance in favor of a healthy gut
  • Enhances Immune Cell Function

 

HOWARU® PROTECT SPORT

HOWARU® Protect Sport is a series of pre-formulated blends developed specifically for sports enthusiasts. It has been clinically shown to support respiratory health and energy levels in physically active adults and to help athletes stay healthy.

10B CFU | 5B CFU Lactobacillus acidophilus (HOWARU NCFM™) + 5B CFU Bifidobacterium lactis (HOWARU Bi-07™)

Benefits

  • Helps physically active adults stay healthy for optimal sports performance
  • Contributes to a significant increase in weekly exercise
  • Supports immune health

 

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Metabolic Health Formulations

HOWARU® SHAPE

HOWARU® Shape is an innovative probiotic solution proven to keep your waist trim without requiring changes to diet or exercise. In a study published in EBioMedicine, HOWARU® Shape (10B CFU B. lactis B420™ alone or in combination with 12g of prebiotic fiber Litesse® Ultra™ polydextrose) controlled body fat mass, trunk fat mass, waist circumference, and reduced energy intake in overweight and obese adults.

10B CFU | Bifidobacterium lactis (HOWARU B420™)​

Benefits

  • Controls body and trunk fat mass
  • Promotes an increase in Akkermansia (linked to lean and healthy body weight)
  • Controls waist circumference

 

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Metabolic Health

Early Life Health Formulations

HOWARU® PROTECT EARLY LIFE

HOWARU® Protect EarlyLife is a safe and proven probiotic formulation that supports the development of the immune system in infants. It has been clinically studied to support overall immunity in infants and children, with documented benefits spanning from birth through age 11.

 

6B CFU | HOWARU® L. rhamnosus HN001™

Benefits

  • Supports immune health to help build baby’s natural defenses
  • Continually supports infant’s and child’s immune system, year after year
  • Provides increased levels of healthy bacteria in the intestinal tract of infants

 

Early Life Health
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