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IMMUNE SUPPORT FOR KIDS: NCFM® AND Bi-07™ INFORMATION

Probiotic effects on cold and influenza-like symptom incidence and duration in children.1

Study aim

To determine the effects of Lactobacillus acidophilus NCFM® or L. acidophilus NCFM® in combination with Bifidobacterium animalis subsp lactis Bi-07™ on cold and influenza-like symptom incidence and duration in healthy children during the winter season (November to May).

Study design

Double-blind, placebo-controlled 

Study method

  • 326 eligible children (3-5 years of age) were assigned randomly to receive:
    • Placebo 
    • NCFM® 10 billion CFU 
    • NCFM® 5 billion CFU and Bi-07™ 5 billion CFU 
  • Children were treated twice daily for 6 months
  • Cold- and flu-like symptoms (fever, cough, rhinorrhea) and other symptoms were monitored for frequency and duration
  • The incidence of illness-related or flu-like symptoms and the number of absences from day care due to illness were also recorded

Study results

NCFM® and Bi-07™ were associated with a reduction in the number of sick days
  • The cumulative number of symptom days was significantly reduced by nearly half (or approximately 3 days) in the probiotic group compared to placebo (P<0.001) 
NCFM® and Bi-07™ were associated with a reduction in symptoms and antibiotic use 
  • Results showed a significant reduction in fever, cough, runny nose, and antibiotic usage in the probiotic group compared to placebo (P≤0.03)

*Results reported are from placebo and NCFM® and Bi-07™ combination; NCFM® alone results not shown.

Bibliography

REFERENCE:

1. Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009;124(2):e172-179.

WHEN PARENTS ARE LOOKING FOR IMMUNE SUPPORT FOR THEIR CHILDREN, RECOMMEND PRODUCTS WITH CLINICALLY RESEARCHED HOWARU® STRAINS NCFM® AND Bi-07™
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