LACTOBACILLUS ACIDOPHILUS
La-14^®

Introduction

Lactobacillus acidophilus La-14® is a lactic acid bacterium of human origin that has been documented in over 50 scientific studies, including 18 clinical trials.  Preclinical studies have shown La-14® can impact both the innate and adaptive immune system.^1,2  These effects and antipathogenic activity are thought to be potential mechanisms behind the efficacy of La-14® combined with HN001™ in women’s health.^3,4 In addition, these two strains together have been shown to support healthy vaginal colonization through oral supplementation.⁵

REFERENCES:
1. Elawadli I, Brisbin JT, Mallard BA, et al. Differential effects of lactobacilli on activation and maturation of mouse dendritic cells. Beneficial Microbes. 2014;5(3):323-334. 2. Paineau D, Carcano D, Leyer G. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. FEMS Immunol Med Microbiol. 2008;53(1):107-113. 3. Bertuccini L, Russo R, Iosi F, Superti F. Effects of Lacticaseibacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. Intl J Immunopathology Pharmacology. 2017;30(2):163-167. 4. Jang SE, Jeong JJ, Choi SY, et al. Lacticaseibacillus rhamnosus HN001™ and Lactobacillus acidophilus La-14® attenuate gardnerella vaginalis-infected bacterial vaginosis in mice. Nutrients. 2017;9:531; doi:10.3390/nu9060531. 5. De Alberti D, Russo R, Terruzzi F, Nobile V, Ouwehand AC. Lactobacilli vaginal colonisation after oral consumption of Respecta® complex: a randomized controlled pilot study. Arch Gynecol Obstet. 2015;292(4):861-867.